GUK1 protein (Octodon degus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

GUK1

Guanylate kinase 1. (225 aa)

Predicted Functional Partners:

GMPS

0.984

ADSL

0.983

ENSODEP00000000138

0.978

GMPR

0.978

PDE6C

0.977

ENTPD3

0.971

DCK

0.970

NT5C1A

0.970

ENTPD8

0.970

HDDC3

0.970

Your Current Organism:

Octodon degus

NCBI taxonomy Id: 10160
Other names: O. degus, degu

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADSL	DCK	ENSODEP00000017118	ENSODEP00000002531	Adenylosuccinate lyase.	Deoxycytidine kinase.	0.610
ADSL	ENSODEP00000000138	ENSODEP00000017118	ENSODEP00000000138	Adenylosuccinate lyase.	annotation not available	0.983
ADSL	ENTPD3	ENSODEP00000017118	ENSODEP00000014858	Adenylosuccinate lyase.	Ectonucleoside triphosphate diphosphohydrolase 3.	0.959
ADSL	ENTPD8	ENSODEP00000017118	ENSODEP00000019507	Adenylosuccinate lyase.	Ectonucleoside triphosphate diphosphohydrolase 8.	0.965
ADSL	GMPR	ENSODEP00000017118	ENSODEP00000006719	Adenylosuccinate lyase.	Guanosine monophosphate reductase.	0.834
ADSL	GMPS	ENSODEP00000017118	ENSODEP00000006764	Adenylosuccinate lyase.	Guanine monophosphate synthase.	0.921
ADSL	GUK1	ENSODEP00000017118	ENSODEP00000001384	Adenylosuccinate lyase.	Guanylate kinase 1.	0.983
ADSL	HDDC3	ENSODEP00000017118	ENSODEP00000021989	Adenylosuccinate lyase.	HD domain containing 3.	0.538
ADSL	NT5C1A	ENSODEP00000017118	ENSODEP00000011045	Adenylosuccinate lyase.	5'-nucleotidase, cytosolic IA.	0.977
ADSL	PDE6C	ENSODEP00000017118	ENSODEP00000020548	Adenylosuccinate lyase.	Phosphodiesterase 6C.	0.755
DCK	ADSL	ENSODEP00000002531	ENSODEP00000017118	Deoxycytidine kinase.	Adenylosuccinate lyase.	0.610
DCK	ENSODEP00000000138	ENSODEP00000002531	ENSODEP00000000138	Deoxycytidine kinase.	annotation not available	0.960
DCK	ENTPD3	ENSODEP00000002531	ENSODEP00000014858	Deoxycytidine kinase.	Ectonucleoside triphosphate diphosphohydrolase 3.	0.565
DCK	ENTPD8	ENSODEP00000002531	ENSODEP00000019507	Deoxycytidine kinase.	Ectonucleoside triphosphate diphosphohydrolase 8.	0.498
DCK	GMPS	ENSODEP00000002531	ENSODEP00000006764	Deoxycytidine kinase.	Guanine monophosphate synthase.	0.530
DCK	GUK1	ENSODEP00000002531	ENSODEP00000001384	Deoxycytidine kinase.	Guanylate kinase 1.	0.970
DCK	NT5C1A	ENSODEP00000002531	ENSODEP00000011045	Deoxycytidine kinase.	5'-nucleotidase, cytosolic IA.	0.975
ENSODEP00000000138	ADSL	ENSODEP00000000138	ENSODEP00000017118	annotation not available	Adenylosuccinate lyase.	0.983
ENSODEP00000000138	DCK	ENSODEP00000000138	ENSODEP00000002531	annotation not available	Deoxycytidine kinase.	0.960
ENSODEP00000000138	ENTPD3	ENSODEP00000000138	ENSODEP00000014858	annotation not available	Ectonucleoside triphosphate diphosphohydrolase 3.	0.961