STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UBE2MUbiquitin conjugating enzyme E2 M. (183 aa)    
Predicted Functional Partners:
DCUN1D5
Defective in cullin neddylation 1 domain containing 5.
    
 0.991
CUL1
Cullin 1.
    
 0.991
NEDD8
NEDD8 ubiquitin like modifier.
   
 0.989
CUL3
Cullin 3.
    
 0.989
ENSODEP00000026090
annotation not available
   
 0.989
ENSODEP00000026680
annotation not available
   
 0.989
ENSODEP00000000769
annotation not available
   
 0.986
ENSODEP00000011191
annotation not available
   
 0.986
UBA1
Ubiquitin like modifier activating enzyme 1.
    
 0.985
CAND1
Cullin associated and neddylation dissociated 1.
    
 0.984
Your Current Organism:
Octodon degus
NCBI taxonomy Id: 10160
Other names: O. degus, degu
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.