Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSODEP00000001515annotation not available (191 aa)    
Predicted Functional Partners:
RAPGEF2
Rap guanine nucleotide exchange factor 2.
    
 0.968
ENSODEP00000010481
annotation not available
    
 0.934
RAPGEF4
Rap guanine nucleotide exchange factor 4.
    
 0.926
AFDN
Afadin, adherens junction formation factor.
    
 0.897
RAPGEF1
Rap guanine nucleotide exchange factor 1.
    
 0.875
RAP1GAP
RAP1 GTPase activating protein.
    
 0.870
ENSODEP00000021735
annotation not available
    
 0.869
ENSODEP00000001281
annotation not available
  
 0.849
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
   
 0.847
ARAF
A-Raf proto-oncogene, serine/threonine kinase.
   
 0.847
Your Current Organism:
Octodon degus
NCBI taxonomy Id: 10160
Other names: O. degus, degu
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.