Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
UBR5Ubiquitin protein ligase E3 component n-recognin 5. (2798 aa)    
Predicted Functional Partners:
ENSODEP00000007187
annotation not available
   
 
 0.957
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
    
   0.950
TP53
Tumor protein p53.
    
 
 0.932
ZUP1
Zinc finger containing ubiquitin peptidase 1.
    
 
 0.931
TRIP12
Thyroid hormone receptor interactor 12.
   
  
 0.931
MCRS1
Microspherule protein 1.
    
   0.930
CEP78
Centrosomal protein 78.
    
 
 0.928
PRPF8
pre-mRNA processing factor 8.
   
 
 0.921
DYRK2
Dual specificity tyrosine phosphorylation regulated kinase 2.
   
 
 0.915
CDC20
Cell division cycle 20.
    
   0.912
Your Current Organism:
Octodon degus
NCBI taxonomy Id: 10160
Other names: O. degus, degu
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