Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AKT2AKT serine/threonine kinase 2. (481 aa)    
Predicted Functional Partners:
AKT1
AKT serine/threonine kinase 1.
   
 0.999
AKT3
AKT serine/threonine kinase 3.
   
 0.998
FOXO1
Forkhead box O1.
    
 0.996
PIK3CA
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha.
   
 0.996
MTOR
Mechanistic target of rapamycin kinase.
    
 0.996
FOXO6
Forkhead box O6.
    
 0.995
FOXO4
Forkhead box O4.
    
 0.995
PDPK1
3-phosphoinositide dependent protein kinase 1.
   
 0.995
TSC2
TSC complex subunit 2.
    
 0.995
PHLPP2
PH domain and leucine rich repeat protein phosphatase 2.
    
 0.995
Your Current Organism:
Octodon degus
NCBI taxonomy Id: 10160
Other names: O. degus, degu
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