OTULIN protein (Octodon degus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

OTULIN

OTU deubiquitinase with linear linkage specificity. (348 aa)

Predicted Functional Partners:

SHARPIN

0.997

ENSODEP00000003859

0.992

RBCK1

0.992

ENSODEP00000026177

0.966

ENSODEP00000026556

0.966

SNX27

0.965

TNF

0.957

OTUD7B

0.911

ENSODEP00000006216

0.901

ENSODEP00000012954

0.901

Your Current Organism:

Octodon degus

NCBI taxonomy Id: 10160
Other names: O. degus, degu

Export your current network:

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same PNG format, but at higher resolution

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSODEP00000003859	ENSODEP00000006216	ENSODEP00000003859	ENSODEP00000006216	annotation not available	annotation not available	0.910
ENSODEP00000003859	ENSODEP00000012954	ENSODEP00000003859	ENSODEP00000012954	annotation not available	annotation not available	0.910
ENSODEP00000003859	ENSODEP00000026177	ENSODEP00000003859	ENSODEP00000026177	annotation not available	annotation not available	0.946
ENSODEP00000003859	ENSODEP00000026556	ENSODEP00000003859	ENSODEP00000026556	annotation not available	annotation not available	0.946
ENSODEP00000003859	OTUD7B	ENSODEP00000003859	ENSODEP00000016204	annotation not available	OTU deubiquitinase 7B.	0.777
ENSODEP00000003859	OTULIN	ENSODEP00000003859	ENSODEP00000001622	annotation not available	OTU deubiquitinase with linear linkage specificity.	0.992
ENSODEP00000003859	RBCK1	ENSODEP00000003859	ENSODEP00000013767	annotation not available	RANBP2-type and C3HC4-type zinc finger containing 1.	0.999
ENSODEP00000003859	SHARPIN	ENSODEP00000003859	ENSODEP00000017486	annotation not available	SHANK associated RH domain interactor.	0.999
ENSODEP00000003859	TNF	ENSODEP00000003859	ENSODEP00000024408	annotation not available	Tumor necrosis factor.	0.985
ENSODEP00000006216	ENSODEP00000003859	ENSODEP00000006216	ENSODEP00000003859	annotation not available	annotation not available	0.910
ENSODEP00000006216	ENSODEP00000026177	ENSODEP00000006216	ENSODEP00000026177	annotation not available	annotation not available	0.985
ENSODEP00000006216	ENSODEP00000026556	ENSODEP00000006216	ENSODEP00000026556	annotation not available	annotation not available	0.980
ENSODEP00000006216	OTUD7B	ENSODEP00000006216	ENSODEP00000016204	annotation not available	OTU deubiquitinase 7B.	0.899
ENSODEP00000006216	OTULIN	ENSODEP00000006216	ENSODEP00000001622	annotation not available	OTU deubiquitinase with linear linkage specificity.	0.901
ENSODEP00000006216	RBCK1	ENSODEP00000006216	ENSODEP00000013767	annotation not available	RANBP2-type and C3HC4-type zinc finger containing 1.	0.899
ENSODEP00000006216	SHARPIN	ENSODEP00000006216	ENSODEP00000017486	annotation not available	SHANK associated RH domain interactor.	0.805
ENSODEP00000006216	TNF	ENSODEP00000006216	ENSODEP00000024408	annotation not available	Tumor necrosis factor.	0.693
ENSODEP00000012954	ENSODEP00000003859	ENSODEP00000012954	ENSODEP00000003859	annotation not available	annotation not available	0.910
ENSODEP00000012954	ENSODEP00000026177	ENSODEP00000012954	ENSODEP00000026177	annotation not available	annotation not available	0.985
ENSODEP00000012954	ENSODEP00000026556	ENSODEP00000012954	ENSODEP00000026556	annotation not available	annotation not available	0.980