HIPK4 protein (Octodon degus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

HIPK4

Homeodomain interacting protein kinase 4. (617 aa)

Predicted Functional Partners:

TP53

0.991

HIPK3

0.986

HIPK2

0.983

RASSF5

0.972

HIPK1

0.866

DAXX

0.859

ENSODEP00000017540

0.855

DCAF7

0.849

ENSODEP00000001318

0.833

ENSODEP00000005810

0.833

Your Current Organism:

Octodon degus

NCBI taxonomy Id: 10160
Other names: O. degus, degu

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DAXX	ENSODEP00000001318	ENSODEP00000023243	ENSODEP00000001318	Death domain associated protein.	annotation not available	0.945
DAXX	ENSODEP00000005810	ENSODEP00000023243	ENSODEP00000005810	Death domain associated protein.	annotation not available	0.945
DAXX	ENSODEP00000017540	ENSODEP00000023243	ENSODEP00000017540	Death domain associated protein.	annotation not available	0.848
DAXX	HIPK1	ENSODEP00000023243	ENSODEP00000009677	Death domain associated protein.	Homeodomain interacting protein kinase 1.	0.859
DAXX	HIPK2	ENSODEP00000023243	ENSODEP00000019039	Death domain associated protein.	Homeodomain interacting protein kinase 2.	0.980
DAXX	HIPK3	ENSODEP00000023243	ENSODEP00000023411	Death domain associated protein.	Homeodomain interacting protein kinase 3.	0.859
DAXX	HIPK4	ENSODEP00000023243	ENSODEP00000001756	Death domain associated protein.	Homeodomain interacting protein kinase 4.	0.859
DAXX	TP53	ENSODEP00000023243	ENSODEP00000024162	Death domain associated protein.	Tumor protein p53.	0.999
DCAF7	HIPK1	ENSODEP00000011218	ENSODEP00000009677	DDB1 and CUL4 associated factor 7.	Homeodomain interacting protein kinase 1.	0.849
DCAF7	HIPK2	ENSODEP00000011218	ENSODEP00000019039	DDB1 and CUL4 associated factor 7.	Homeodomain interacting protein kinase 2.	0.917
DCAF7	HIPK3	ENSODEP00000011218	ENSODEP00000023411	DDB1 and CUL4 associated factor 7.	Homeodomain interacting protein kinase 3.	0.849
DCAF7	HIPK4	ENSODEP00000011218	ENSODEP00000001756	DDB1 and CUL4 associated factor 7.	Homeodomain interacting protein kinase 4.	0.849
ENSODEP00000001318	DAXX	ENSODEP00000001318	ENSODEP00000023243	annotation not available	Death domain associated protein.	0.945
ENSODEP00000001318	ENSODEP00000017540	ENSODEP00000001318	ENSODEP00000017540	annotation not available	annotation not available	0.875
ENSODEP00000001318	HIPK1	ENSODEP00000001318	ENSODEP00000009677	annotation not available	Homeodomain interacting protein kinase 1.	0.833
ENSODEP00000001318	HIPK2	ENSODEP00000001318	ENSODEP00000019039	annotation not available	Homeodomain interacting protein kinase 2.	0.934
ENSODEP00000001318	HIPK3	ENSODEP00000001318	ENSODEP00000023411	annotation not available	Homeodomain interacting protein kinase 3.	0.833
ENSODEP00000001318	HIPK4	ENSODEP00000001318	ENSODEP00000001756	annotation not available	Homeodomain interacting protein kinase 4.	0.833
ENSODEP00000001318	TP53	ENSODEP00000001318	ENSODEP00000024162	annotation not available	Tumor protein p53.	0.926
ENSODEP00000005810	DAXX	ENSODEP00000005810	ENSODEP00000023243	annotation not available	Death domain associated protein.	0.945