PRRG3 protein (Octodon degus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

PRRG3

Proline rich and Gla domain 3. (230 aa)

Predicted Functional Partners:

NEDD4L

0.885

NEDD4

0.869

NDFIP1

0.838

NDFIP2

0.685

ENSODEP00000012319

0.630

HECW1

0.630

ENSODEP00000010389

0.591

ENSODEP00000021282

0.584

LRRC52

0.547

RNASE10

0.530

Your Current Organism:

Octodon degus

NCBI taxonomy Id: 10160
Other names: O. degus, degu

Export your current network:

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same PNG format, but at higher resolution

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSODEP00000010389	PRRG3	ENSODEP00000010389	ENSODEP00000001941	annotation not available	Proline rich and Gla domain 3.	0.591
ENSODEP00000012319	HECW1	ENSODEP00000012319	ENSODEP00000012785	annotation not available	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1.	0.675
ENSODEP00000012319	NDFIP1	ENSODEP00000012319	ENSODEP00000016960	annotation not available	Nedd4 family interacting protein 1.	0.834
ENSODEP00000012319	NDFIP2	ENSODEP00000012319	ENSODEP00000007385	annotation not available	Nedd4 family interacting protein 2.	0.786
ENSODEP00000012319	NEDD4	ENSODEP00000012319	ENSODEP00000009108	annotation not available	NEDD4 E3 ubiquitin protein ligase.	0.693
ENSODEP00000012319	NEDD4L	ENSODEP00000012319	ENSODEP00000025266	annotation not available	NEDD4 like E3 ubiquitin protein ligase.	0.566
ENSODEP00000012319	PRRG3	ENSODEP00000012319	ENSODEP00000001941	annotation not available	Proline rich and Gla domain 3.	0.630
ENSODEP00000021282	LRRC52	ENSODEP00000021282	ENSODEP00000010153	annotation not available	Leucine rich repeat containing 52.	0.593
ENSODEP00000021282	PRRG3	ENSODEP00000021282	ENSODEP00000001941	annotation not available	Proline rich and Gla domain 3.	0.584
HECW1	ENSODEP00000012319	ENSODEP00000012785	ENSODEP00000012319	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1.	annotation not available	0.675
HECW1	NDFIP1	ENSODEP00000012785	ENSODEP00000016960	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1.	Nedd4 family interacting protein 1.	0.876
HECW1	NDFIP2	ENSODEP00000012785	ENSODEP00000007385	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1.	Nedd4 family interacting protein 2.	0.786
HECW1	PRRG3	ENSODEP00000012785	ENSODEP00000001941	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1.	Proline rich and Gla domain 3.	0.630
LRRC52	ENSODEP00000021282	ENSODEP00000010153	ENSODEP00000021282	Leucine rich repeat containing 52.	annotation not available	0.593
LRRC52	PRRG3	ENSODEP00000010153	ENSODEP00000001941	Leucine rich repeat containing 52.	Proline rich and Gla domain 3.	0.547
NDFIP1	ENSODEP00000012319	ENSODEP00000016960	ENSODEP00000012319	Nedd4 family interacting protein 1.	annotation not available	0.834
NDFIP1	HECW1	ENSODEP00000016960	ENSODEP00000012785	Nedd4 family interacting protein 1.	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1.	0.876
NDFIP1	NDFIP2	ENSODEP00000016960	ENSODEP00000007385	Nedd4 family interacting protein 1.	Nedd4 family interacting protein 2.	0.672
NDFIP1	NEDD4	ENSODEP00000016960	ENSODEP00000009108	Nedd4 family interacting protein 1.	NEDD4 E3 ubiquitin protein ligase.	0.986
NDFIP1	NEDD4L	ENSODEP00000016960	ENSODEP00000025266	Nedd4 family interacting protein 1.	NEDD4 like E3 ubiquitin protein ligase.	0.936