EPHA5 protein (Octodon degus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

EPHA5

EPH receptor A5. (1032 aa)

Predicted Functional Partners:

EFNA5

0.992

EFNA4

0.990

EFNA2

0.990

EFNA1

0.989

EFNA3

0.988

RASA1

0.974

EFNB3

0.974

NGEF

0.973

EFNB2

0.973

EFNB1

0.932

Your Current Organism:

Octodon degus

NCBI taxonomy Id: 10160
Other names: O. degus, degu

Export your current network:

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file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

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same PNG format, but at higher resolution

... as a vector graphic:

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EFNA1	EFNA2	ENSODEP00000013595	ENSODEP00000017331	Ephrin A1.	Ephrin A2.	0.602
EFNA1	EFNA3	ENSODEP00000013595	ENSODEP00000014151	Ephrin A1.	Ephrin A3.	0.916
EFNA1	EFNA4	ENSODEP00000013595	ENSODEP00000015814	Ephrin A1.	Ephrin A4.	0.874
EFNA1	EFNA5	ENSODEP00000013595	ENSODEP00000018548	Ephrin A1.	Ephrin A5.	0.959
EFNA1	EFNB1	ENSODEP00000013595	ENSODEP00000004286	Ephrin A1.	Ephrin B1.	0.773
EFNA1	EFNB2	ENSODEP00000013595	ENSODEP00000013810	Ephrin A1.	Ephrin B2.	0.821
EFNA1	EFNB3	ENSODEP00000013595	ENSODEP00000024146	Ephrin A1.	Ephrin B3.	0.767
EFNA1	EPHA5	ENSODEP00000013595	ENSODEP00000001967	Ephrin A1.	EPH receptor A5.	0.989
EFNA1	NGEF	ENSODEP00000013595	ENSODEP00000010989	Ephrin A1.	Neuronal guanine nucleotide exchange factor.	0.585
EFNA1	RASA1	ENSODEP00000013595	ENSODEP00000007255	Ephrin A1.	RAS p21 protein activator 1.	0.963
EFNA2	EFNA1	ENSODEP00000017331	ENSODEP00000013595	Ephrin A2.	Ephrin A1.	0.602
EFNA2	EFNA3	ENSODEP00000017331	ENSODEP00000014151	Ephrin A2.	Ephrin A3.	0.595
EFNA2	EFNA4	ENSODEP00000017331	ENSODEP00000015814	Ephrin A2.	Ephrin A4.	0.604
EFNA2	EFNA5	ENSODEP00000017331	ENSODEP00000018548	Ephrin A2.	Ephrin A5.	0.743
EFNA2	EFNB1	ENSODEP00000017331	ENSODEP00000004286	Ephrin A2.	Ephrin B1.	0.831
EFNA2	EFNB2	ENSODEP00000017331	ENSODEP00000013810	Ephrin A2.	Ephrin B2.	0.858
EFNA2	EFNB3	ENSODEP00000017331	ENSODEP00000024146	Ephrin A2.	Ephrin B3.	0.796
EFNA2	EPHA5	ENSODEP00000017331	ENSODEP00000001967	Ephrin A2.	EPH receptor A5.	0.990
EFNA2	NGEF	ENSODEP00000017331	ENSODEP00000010989	Ephrin A2.	Neuronal guanine nucleotide exchange factor.	0.555
EFNA2	RASA1	ENSODEP00000017331	ENSODEP00000007255	Ephrin A2.	RAS p21 protein activator 1.	0.960