STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADAM22ADAM metallopeptidase domain 22. (903 aa)    
Predicted Functional Partners:
LGI1
Leucine rich glioma inactivated 1.
   
 0.992
DLG4
Discs large MAGUK scaffold protein 4.
   
 0.989
LGI2
Leucine rich repeat LGI family member 2.
     
 0.963
ADAM23
ADAM metallopeptidase domain 23.
   
 0.956
SYNGAP1
Synaptic Ras GTPase activating protein 1.
   
 
 0.903
DLG2
Discs large MAGUK scaffold protein 2.
   
 0.888
DLG1
Discs large MAGUK scaffold protein 1.
   
 0.888
DLG3
Discs large MAGUK scaffold protein 3.
   
 0.885
LGI4
Leucine rich repeat LGI family member 4.
     
 0.841
CACNG2
Calcium voltage-gated channel auxiliary subunit gamma 2.
     
 0.831
Your Current Organism:
Octodon degus
NCBI taxonomy Id: 10160
Other names: O. degus, degu
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.