REM2 protein (Octodon degus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

REM2

RRAD and GEM like GTPase 2. (340 aa)

Predicted Functional Partners:

CA10

0.885

NOS1AP

0.845

ENSODEP00000025351

0.844

ENSODEP00000010090

0.830

ENSODEP00000010785

0.830

TSC2

0.814

DOCK4

0.809

MET

0.799

ENSODEP00000024866

0.799

SHANK3

0.791

Your Current Organism:

Octodon degus

NCBI taxonomy Id: 10160
Other names: O. degus, degu

Export your current network:

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same PNG format, but at higher resolution

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CA10	NOS1AP	ENSODEP00000022095	ENSODEP00000012518	Carbonic anhydrase 10.	Nitric oxide synthase 1 adaptor protein.	0.525
CA10	REM2	ENSODEP00000022095	ENSODEP00000002104	Carbonic anhydrase 10.	RRAD and GEM like GTPase 2.	0.885
DOCK4	ENSODEP00000025351	ENSODEP00000010135	ENSODEP00000025351	Dedicator of cytokinesis 4.	annotation not available	0.609
DOCK4	REM2	ENSODEP00000010135	ENSODEP00000002104	Dedicator of cytokinesis 4.	RRAD and GEM like GTPase 2.	0.809
DOCK4	SHANK3	ENSODEP00000010135	ENSODEP00000021410	Dedicator of cytokinesis 4.	SH3 and multiple ankyrin repeat domains 3.	0.462
ENSODEP00000010090	ENSODEP00000010785	ENSODEP00000010090	ENSODEP00000010785	annotation not available	annotation not available	0.976
ENSODEP00000010090	ENSODEP00000024866	ENSODEP00000010090	ENSODEP00000024866	annotation not available	annotation not available	0.696
ENSODEP00000010090	ENSODEP00000025351	ENSODEP00000010090	ENSODEP00000025351	annotation not available	annotation not available	0.961
ENSODEP00000010090	MET	ENSODEP00000010090	ENSODEP00000001269	annotation not available	MET proto-oncogene, receptor tyrosine kinase.	0.696
ENSODEP00000010090	NOS1AP	ENSODEP00000010090	ENSODEP00000012518	annotation not available	Nitric oxide synthase 1 adaptor protein.	0.737
ENSODEP00000010090	REM2	ENSODEP00000010090	ENSODEP00000002104	annotation not available	RRAD and GEM like GTPase 2.	0.830
ENSODEP00000010090	SHANK3	ENSODEP00000010090	ENSODEP00000021410	annotation not available	SH3 and multiple ankyrin repeat domains 3.	0.515
ENSODEP00000010785	ENSODEP00000010090	ENSODEP00000010785	ENSODEP00000010090	annotation not available	annotation not available	0.976
ENSODEP00000010785	ENSODEP00000024866	ENSODEP00000010785	ENSODEP00000024866	annotation not available	annotation not available	0.696
ENSODEP00000010785	ENSODEP00000025351	ENSODEP00000010785	ENSODEP00000025351	annotation not available	annotation not available	0.961
ENSODEP00000010785	MET	ENSODEP00000010785	ENSODEP00000001269	annotation not available	MET proto-oncogene, receptor tyrosine kinase.	0.696
ENSODEP00000010785	NOS1AP	ENSODEP00000010785	ENSODEP00000012518	annotation not available	Nitric oxide synthase 1 adaptor protein.	0.737
ENSODEP00000010785	REM2	ENSODEP00000010785	ENSODEP00000002104	annotation not available	RRAD and GEM like GTPase 2.	0.830
ENSODEP00000010785	SHANK3	ENSODEP00000010785	ENSODEP00000021410	annotation not available	SH3 and multiple ankyrin repeat domains 3.	0.515
ENSODEP00000024866	ENSODEP00000010090	ENSODEP00000024866	ENSODEP00000010090	annotation not available	annotation not available	0.696