STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADAM17ADAM metallopeptidase domain 17. (841 aa)    
Predicted Functional Partners:
TIMP3
TIMP metallopeptidase inhibitor 3.
    
 0.974
ADAM10
ADAM metallopeptidase domain 10.
     
0.947
NOTCH1
Notch receptor 1.
    
 0.946
TIMP2
TIMP metallopeptidase inhibitor 2.
    
 0.935
NOTCH2
Notch receptor 2.
    
 0.931
RHBDF2
Rhomboid 5 homolog 2.
    
 0.903
NOTCH3
Notch receptor 3.
    
 0.877
ENSODEP00000024125
annotation not available
    
 0.876
RHBDF1
Rhomboid 5 homolog 1.
    
 0.867
HBEGF
Heparin binding EGF like growth factor.
     
 0.865
Your Current Organism:
Octodon degus
NCBI taxonomy Id: 10160
Other names: O. degus, degu
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.