STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IRAK3Interleukin 1 receptor associated kinase 3. (550 aa)    
Predicted Functional Partners:
IRAK1
Interleukin 1 receptor associated kinase 1.
  
 
0.988
TRAF6
TNF receptor associated factor 6.
   
 0.984
IRAK2
Interleukin 1 receptor associated kinase 2.
    
0.984
ENSODEP00000025351
annotation not available
   
 0.939
ENSODEP00000025646
annotation not available
    
 0.939
TRAF7
TNF receptor associated factor 7.
   
 0.937
MYD88
MYD88 innate immune signal transduction adaptor.
   
 0.895
ENSODEP00000011836
annotation not available
    
 0.867
ENSODEP00000012279
annotation not available
    
 0.867
IL1R1
Interleukin 1 receptor type 1.
   
 0.864
Your Current Organism:
Octodon degus
NCBI taxonomy Id: 10160
Other names: O. degus, degu
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.