STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERBB3Erb-b2 receptor tyrosine kinase 3. (1337 aa)    
Predicted Functional Partners:
NRG1
Neuregulin 1.
    
 0.998
ERBB2
Erb-b2 receptor tyrosine kinase 2.
  
 
0.998
EGFR
Epidermal growth factor receptor.
  
 
0.996
SHC1
SHC adaptor protein 1.
    
 0.996
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
    
 0.996
LOC101563936
annotation not available
    
 0.990
MET
MET proto-oncogene, receptor tyrosine kinase.
   
0.990
ENSODEP00000013691
annotation not available
    
 0.990
ENSODEP00000013265
annotation not available
   
 0.989
SHC3
SHC adaptor protein 3.
    
 0.988
Your Current Organism:
Octodon degus
NCBI taxonomy Id: 10160
Other names: O. degus, degu
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.