STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HECW1HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1. (1545 aa)    
Predicted Functional Partners:
ENSODEP00000026177
annotation not available
    
 0.947
ENSODEP00000026556
annotation not available
    
 0.947
SMAD6
SMAD family member 6.
    
 0.943
SMAD7
SMAD family member 7.
    
 0.943
LATS1
Large tumor suppressor kinase 1.
    
 0.920
LATS2
Large tumor suppressor kinase 2.
    
 0.920
ENSODEP00000024149
annotation not available
   
 0.918
ENSODEP00000006216
annotation not available
    
 0.914
ENSODEP00000012954
annotation not available
    
 0.914
Rps27a
annotation not available
    
 0.914
Your Current Organism:
Octodon degus
NCBI taxonomy Id: 10160
Other names: O. degus, degu
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.