STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
JAK3Janus kinase 3. (1103 aa)    
Predicted Functional Partners:
SOCS3
Suppressor of cytokine signaling 3.
   
 0.992
EPOR
Erythropoietin receptor.
    
 0.991
LEPR
Leptin receptor.
    
 0.989
SOCS1
Suppressor of cytokine signaling 1.
   
 0.989
CSF2RB
Colony stimulating factor 2 receptor beta common subunit.
   
 0.981
STAT6
Signal transducer and activator of transcription 6.
   
 0.980
ENSODEP00000008783
annotation not available
   
 0.980
STAT1
Signal transducer and activator of transcription 1.
   
 0.980
ENSODEP00000024549
annotation not available
   
 0.980
GHR
Growth hormone receptor.
    
 0.979
Your Current Organism:
Octodon degus
NCBI taxonomy Id: 10160
Other names: O. degus, degu
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.