IRF5 protein (Octodon degus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

IRF5

Interferon regulatory factor 5. (499 aa)

Predicted Functional Partners:

TRAF6

0.975

ENSODEP00000018298

0.908

STING1

0.868

CREBBP

0.848

ENSODEP00000018175

0.843

MYD88

0.838

ENSODEP00000017540

0.836

ENSODEP00000017898

0.831

SGK3

0.825

RIPK4

0.805

Your Current Organism:

Octodon degus

NCBI taxonomy Id: 10160
Other names: O. degus, degu

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CREBBP	ENSODEP00000017540	ENSODEP00000019124	ENSODEP00000017540	CREB binding protein.	annotation not available	0.998
CREBBP	IRF5	ENSODEP00000019124	ENSODEP00000018281	CREB binding protein.	Interferon regulatory factor 5.	0.848
CREBBP	MYD88	ENSODEP00000019124	ENSODEP00000011150	CREB binding protein.	MYD88 innate immune signal transduction adaptor.	0.898
CREBBP	RIPK4	ENSODEP00000019124	ENSODEP00000018690	CREB binding protein.	Receptor interacting serine/threonine kinase 4.	0.566
ENSODEP00000017540	CREBBP	ENSODEP00000017540	ENSODEP00000019124	annotation not available	CREB binding protein.	0.998
ENSODEP00000017540	IRF5	ENSODEP00000017540	ENSODEP00000018281	annotation not available	Interferon regulatory factor 5.	0.836
ENSODEP00000017540	MYD88	ENSODEP00000017540	ENSODEP00000011150	annotation not available	MYD88 innate immune signal transduction adaptor.	0.805
ENSODEP00000017540	RIPK4	ENSODEP00000017540	ENSODEP00000018690	annotation not available	Receptor interacting serine/threonine kinase 4.	0.566
ENSODEP00000017898	ENSODEP00000018175	ENSODEP00000017898	ENSODEP00000018175	annotation not available	annotation not available	0.975
ENSODEP00000017898	ENSODEP00000018298	ENSODEP00000017898	ENSODEP00000018298	annotation not available	annotation not available	0.991
ENSODEP00000017898	IRF5	ENSODEP00000017898	ENSODEP00000018281	annotation not available	Interferon regulatory factor 5.	0.831
ENSODEP00000018175	ENSODEP00000017898	ENSODEP00000018175	ENSODEP00000017898	annotation not available	annotation not available	0.975
ENSODEP00000018175	ENSODEP00000018298	ENSODEP00000018175	ENSODEP00000018298	annotation not available	annotation not available	0.974
ENSODEP00000018175	IRF5	ENSODEP00000018175	ENSODEP00000018281	annotation not available	Interferon regulatory factor 5.	0.843
ENSODEP00000018298	ENSODEP00000017898	ENSODEP00000018298	ENSODEP00000017898	annotation not available	annotation not available	0.991
ENSODEP00000018298	ENSODEP00000018175	ENSODEP00000018298	ENSODEP00000018175	annotation not available	annotation not available	0.974
ENSODEP00000018298	IRF5	ENSODEP00000018298	ENSODEP00000018281	annotation not available	Interferon regulatory factor 5.	0.908
IRF5	CREBBP	ENSODEP00000018281	ENSODEP00000019124	Interferon regulatory factor 5.	CREB binding protein.	0.848
IRF5	ENSODEP00000017540	ENSODEP00000018281	ENSODEP00000017540	Interferon regulatory factor 5.	annotation not available	0.836
IRF5	ENSODEP00000017898	ENSODEP00000018281	ENSODEP00000017898	Interferon regulatory factor 5.	annotation not available	0.831