FASLG protein (Octodon degus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

FASLG

Fas ligand. (274 aa)

Predicted Functional Partners:

ENSODEP00000018854

0.987

ENSODEP00000021380

0.987

Fau

0.987

CASP8

0.976

PRF1

0.927

CD40LG

0.925

LUM

0.920

FOXO4

0.896

ENSODEP00000016525

0.893

ENSODEP00000025735

0.893

Your Current Organism:

Octodon degus

NCBI taxonomy Id: 10160
Other names: O. degus, degu

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CASP8	ENSODEP00000018854	ENSODEP00000012216	ENSODEP00000018854	Caspase 8.	annotation not available	0.485
CASP8	ENSODEP00000021380	ENSODEP00000012216	ENSODEP00000021380	Caspase 8.	annotation not available	0.485
CASP8	FASLG	ENSODEP00000012216	ENSODEP00000018527	Caspase 8.	Fas ligand.	0.976
CASP8	Fau	ENSODEP00000012216	ENSODEP00000024490	Caspase 8.	annotation not available	0.485
CD40LG	FASLG	ENSODEP00000003860	ENSODEP00000018527	CD40 ligand.	Fas ligand.	0.925
CD40LG	PRF1	ENSODEP00000003860	ENSODEP00000020490	CD40 ligand.	Perforin 1.	0.447
ENSODEP00000016525	ENSODEP00000018854	ENSODEP00000016525	ENSODEP00000018854	annotation not available	annotation not available	0.999
ENSODEP00000016525	ENSODEP00000021380	ENSODEP00000016525	ENSODEP00000021380	annotation not available	annotation not available	0.999
ENSODEP00000016525	FASLG	ENSODEP00000016525	ENSODEP00000018527	annotation not available	Fas ligand.	0.893
ENSODEP00000016525	Fau	ENSODEP00000016525	ENSODEP00000024490	annotation not available	annotation not available	0.999
ENSODEP00000018854	CASP8	ENSODEP00000018854	ENSODEP00000012216	annotation not available	Caspase 8.	0.485
ENSODEP00000018854	ENSODEP00000016525	ENSODEP00000018854	ENSODEP00000016525	annotation not available	annotation not available	0.999
ENSODEP00000018854	ENSODEP00000021380	ENSODEP00000018854	ENSODEP00000021380	annotation not available	annotation not available	0.998
ENSODEP00000018854	ENSODEP00000025735	ENSODEP00000018854	ENSODEP00000025735	annotation not available	annotation not available	0.999
ENSODEP00000018854	FASLG	ENSODEP00000018854	ENSODEP00000018527	annotation not available	Fas ligand.	0.987
ENSODEP00000018854	Fau	ENSODEP00000018854	ENSODEP00000024490	annotation not available	annotation not available	0.998
ENSODEP00000021380	CASP8	ENSODEP00000021380	ENSODEP00000012216	annotation not available	Caspase 8.	0.485
ENSODEP00000021380	ENSODEP00000016525	ENSODEP00000021380	ENSODEP00000016525	annotation not available	annotation not available	0.999
ENSODEP00000021380	ENSODEP00000018854	ENSODEP00000021380	ENSODEP00000018854	annotation not available	annotation not available	0.998
ENSODEP00000021380	ENSODEP00000025735	ENSODEP00000021380	ENSODEP00000025735	annotation not available	annotation not available	0.999