STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPI1Spi-1 proto-oncogene. (283 aa)    
Predicted Functional Partners:
CSF1R
Colony stimulating factor 1 receptor.
   
 
 0.949
KIT
KIT proto-oncogene, receptor tyrosine kinase.
   
 
 0.920
GATA2
GATA binding protein 2.
    
 0.904
RARA
Retinoic acid receptor alpha.
    
 0.904
CSF3R
Colony stimulating factor 3 receptor.
   
 0.896
ITGAM
Integrin subunit alpha M.
   
 
 0.894
IRF4
Interferon regulatory factor 4.
   
 
 0.891
FLT3
Fms related tyrosine kinase 3.
     
 0.882
CBFA2T3
CBFA2/RUNX1 partner transcriptional co-repressor 3.
    
 0.880
RUNX1T1
RUNX1 partner transcriptional co-repressor 1.
    
 0.878
Your Current Organism:
Octodon degus
NCBI taxonomy Id: 10160
Other names: O. degus, degu
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.