TNF protein (Octodon degus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

TNF

Tumor necrosis factor. (234 aa)

Predicted Functional Partners:

TNFRSF1B

0.998

TNFRSF1A

0.997

TNFAIP3

0.996

ENSODEP00000006503

0.993

RIPK1

0.993

TRAF2

0.993

TRADD

0.993

IKBKG

0.992

CHUK

0.992

IKBKE

0.991

Your Current Organism:

Octodon degus

NCBI taxonomy Id: 10160
Other names: O. degus, degu

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHUK	ENSODEP00000006503	ENSODEP00000022589	ENSODEP00000006503	Component of inhibitor of nuclear factor kappa B kinase complex.	annotation not available	0.998
CHUK	IKBKE	ENSODEP00000022589	ENSODEP00000008004	Component of inhibitor of nuclear factor kappa B kinase complex.	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	0.740
CHUK	IKBKG	ENSODEP00000022589	ENSODEP00000007932	Component of inhibitor of nuclear factor kappa B kinase complex.	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	0.997
CHUK	RIPK1	ENSODEP00000022589	ENSODEP00000010259	Component of inhibitor of nuclear factor kappa B kinase complex.	Receptor interacting serine/threonine kinase 1.	0.978
CHUK	TNF	ENSODEP00000022589	ENSODEP00000024408	Component of inhibitor of nuclear factor kappa B kinase complex.	Tumor necrosis factor.	0.992
CHUK	TNFAIP3	ENSODEP00000022589	ENSODEP00000012032	Component of inhibitor of nuclear factor kappa B kinase complex.	TNF alpha induced protein 3.	0.876
CHUK	TNFRSF1A	ENSODEP00000022589	ENSODEP00000006504	Component of inhibitor of nuclear factor kappa B kinase complex.	TNF receptor superfamily member 1A.	0.995
CHUK	TRADD	ENSODEP00000022589	ENSODEP00000022168	Component of inhibitor of nuclear factor kappa B kinase complex.	TNFRSF1A associated via death domain.	0.962
CHUK	TRAF2	ENSODEP00000022589	ENSODEP00000021072	Component of inhibitor of nuclear factor kappa B kinase complex.	TNF receptor associated factor 2.	0.991
ENSODEP00000006503	CHUK	ENSODEP00000006503	ENSODEP00000022589	annotation not available	Component of inhibitor of nuclear factor kappa B kinase complex.	0.998
ENSODEP00000006503	IKBKE	ENSODEP00000006503	ENSODEP00000008004	annotation not available	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	0.683
ENSODEP00000006503	IKBKG	ENSODEP00000006503	ENSODEP00000007932	annotation not available	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	0.998
ENSODEP00000006503	RIPK1	ENSODEP00000006503	ENSODEP00000010259	annotation not available	Receptor interacting serine/threonine kinase 1.	0.972
ENSODEP00000006503	TNF	ENSODEP00000006503	ENSODEP00000024408	annotation not available	Tumor necrosis factor.	0.993
ENSODEP00000006503	TNFAIP3	ENSODEP00000006503	ENSODEP00000012032	annotation not available	TNF alpha induced protein 3.	0.935
ENSODEP00000006503	TNFRSF1A	ENSODEP00000006503	ENSODEP00000006504	annotation not available	TNF receptor superfamily member 1A.	0.998
ENSODEP00000006503	TRADD	ENSODEP00000006503	ENSODEP00000022168	annotation not available	TNFRSF1A associated via death domain.	0.953
ENSODEP00000006503	TRAF2	ENSODEP00000006503	ENSODEP00000021072	annotation not available	TNF receptor associated factor 2.	0.989
IKBKE	CHUK	ENSODEP00000008004	ENSODEP00000022589	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	Component of inhibitor of nuclear factor kappa B kinase complex.	0.740
IKBKE	ENSODEP00000006503	ENSODEP00000008004	ENSODEP00000006503	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	annotation not available	0.683