GW7_21815 protein (Heterocephalus glaber) - STRING interaction network

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Score

GW7_21815

Tudor domain-containing protein 3. (609 aa)

Predicted Functional Partners:

Wrn

0.980

GW7_10415

0.940

TOP3B

0.911

Znf462

0.885

GW7_07661

0.868

Mus81

0.754

Rpa3

0.738

Blm

0.734

Recql4

0.734

Recql5

0.694

Your Current Organism:

Heterocephalus glaber

NCBI taxonomy Id: 10181
Other names: H. glaber, naked mole rat, naked mole-rat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Blm	GW7_07661	G5B1S9	G5BMX8	Bloom syndrome protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.996
Blm	GW7_10415	G5B1S9	G5BUQ8	Bloom syndrome protein.	Fanconi anemia group M protein.	0.994
Blm	GW7_21815	G5B1S9	G5AKH7	Bloom syndrome protein.	Tudor domain-containing protein 3.	0.734
Blm	Mus81	G5B1S9	G5B6I9	Bloom syndrome protein.	Crossover junction endonuclease MUS81.	0.968
Blm	Recql5	G5B1S9	G5BNA8	Bloom syndrome protein.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.422
Blm	Rpa3	G5B1S9	G5BRY8	Bloom syndrome protein.	Replication protein A 14 kDa subunit.	0.997
Blm	TOP3B	G5B1S9	G5BKF9	Bloom syndrome protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.972
Blm	Wrn	G5B1S9	G5C9Z1	Bloom syndrome protein.	Werner syndrome ATP-dependent helicase.	0.693
GW7_07661	Blm	G5BMX8	G5B1S9	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	Bloom syndrome protein.	0.996
GW7_07661	GW7_10415	G5BMX8	G5BUQ8	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	Fanconi anemia group M protein.	0.994
GW7_07661	GW7_21815	G5BMX8	G5AKH7	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	Tudor domain-containing protein 3.	0.868
GW7_07661	Mus81	G5BMX8	G5B6I9	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	Crossover junction endonuclease MUS81.	0.932
GW7_07661	Recql4	G5BMX8	G5C5R6	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	ATP-dependent DNA helicase Q4.	0.970
GW7_07661	Recql5	G5BMX8	G5BNA8	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.891
GW7_07661	Rpa3	G5BMX8	G5BRY8	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	Replication protein A 14 kDa subunit.	0.976
GW7_07661	Wrn	G5BMX8	G5C9Z1	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	Werner syndrome ATP-dependent helicase.	0.999
GW7_10415	Blm	G5BUQ8	G5B1S9	Fanconi anemia group M protein.	Bloom syndrome protein.	0.994
GW7_10415	GW7_07661	G5BUQ8	G5BMX8	Fanconi anemia group M protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.994
GW7_10415	GW7_21815	G5BUQ8	G5AKH7	Fanconi anemia group M protein.	Tudor domain-containing protein 3.	0.940
GW7_10415	Mus81	G5BUQ8	G5B6I9	Fanconi anemia group M protein.	Crossover junction endonuclease MUS81.	0.999