STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dram1DNA damage-regulated autophagy modulator protein 1. (198 aa)    
Predicted Functional Partners:
Flvcr2
Feline leukemia virus subgroup C receptor-related protein 2.
      
 0.546
Mest
Mesoderm-specific transcript-like protein.
      
 0.536
LRAT
Lecithin retinol acyltransferase.
      
 0.534
GW7_12428
Paraplegin.
      
 0.479
Tp53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
      
 0.457
Mcm5
DNA helicase; Belongs to the MCM family.
      
 0.454
Coro1a
Coronin; Belongs to the WD repeat coronin family.
      
 0.452
GW7_02492
Tetratricopeptide repeat protein 12.
      
 0.451
Your Current Organism:
Heterocephalus glaber
NCBI taxonomy Id: 10181
Other names: H. glaber, naked mole rat, naked mole-rat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.