STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPG21Maspardin isoform b. (308 aa)    
Predicted Functional Partners:
GW7_12428
Paraplegin.
      
 0.679
Spg11
Spatacsin.
      
 0.679
SPG20
Spartin.
      
 0.642
Aldh16a1
Aldehyde dehydrogenase family 16 member A1.
      
 0.601
TNFSF15
Tumor necrosis factor ligand superfamily member 15 isoform VEGI-251.
      
 0.588
Nipa1
Magnesium transporter NIPA1.
      
 0.571
Ap5z1
Fork-head domain-containing protein.
      
 0.536
GW7_07373
Neuropathy target esterase.
      
 0.512
Gpc3
Glypican-3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
      
 0.476
Dera
Putative deoxyribose-phosphate aldolase.
      
 0.452
Your Current Organism:
Heterocephalus glaber
NCBI taxonomy Id: 10181
Other names: H. glaber, naked mole rat, naked mole-rat
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.