STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Adra2bAlpha-2B adrenergic receptor. (444 aa)    
Predicted Functional Partners:
Gna13
Guanine nucleotide-binding protein subunit alpha-13.
    
 0.922
Gna12
Guanine nucleotide-binding protein subunit alpha-12.
    
 0.922
Gna11
Guanine nucleotide-binding protein subunit alpha-11.
    
 0.919
Gnaq
Guanine nucleotide-binding protein G(Q) subunit alpha.
    
 0.919
Ghr
Growth hormone receptor.
      
 0.855
Rag1
V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...]
      
 0.855
Vwf
Von Willebrand factor.
    
 0.751
GW7_03288
Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.
      
 0.678
GW7_04217
Guanine nucleotide-binding protein subunit beta-5.
    
 0.656
Gnb3
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3.
    
 0.618
Your Current Organism:
Heterocephalus glaber
NCBI taxonomy Id: 10181
Other names: H. glaber, naked mole rat, naked mole-rat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.