Rnf14 protein (Heterocephalus glaber) - STRING interaction network

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Score

Rnf14

RBR-type E3 ubiquitin transferase. (461 aa)

Predicted Functional Partners:

GW7_21478

0.687

Atg7

0.507

Fbxo18

0.471

Rnf6

0.455

MED31

0.453

Gspt1

0.435

Gspt2

0.435

Fbxw2

0.419

Ube2v1

0.413

Rnf216

0.408

Your Current Organism:

Heterocephalus glaber

NCBI taxonomy Id: 10181
Other names: H. glaber, naked mole rat, naked mole-rat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Atg7	Fbxw2	G5C223	G5CAF5	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	F-box/WD repeat-containing protein 2.	0.429
Atg7	Rnf14	G5C223	G5AQR5	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	RBR-type E3 ubiquitin transferase.	0.507
Atg7	Rnf6	G5C223	G5AMX7	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	RING finger protein 6.	0.471
Atg7	Ube2v1	G5C223	G5AZ04	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Transmembrane protein 189.	0.951
Fbxo18	Fbxw2	G5BP97	G5CAF5	F-box only protein 18.	F-box/WD repeat-containing protein 2.	0.453
Fbxo18	MED31	G5BP97	G5B909	F-box only protein 18.	Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.500
Fbxo18	Rnf14	G5BP97	G5AQR5	F-box only protein 18.	RBR-type E3 ubiquitin transferase.	0.471
Fbxo18	Rnf6	G5BP97	G5AMX7	F-box only protein 18.	RING finger protein 6.	0.419
Fbxo18	Ube2v1	G5BP97	G5AZ04	F-box only protein 18.	Transmembrane protein 189.	0.594
Fbxw2	Atg7	G5CAF5	G5C223	F-box/WD repeat-containing protein 2.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.429
Fbxw2	Fbxo18	G5CAF5	G5BP97	F-box/WD repeat-containing protein 2.	F-box only protein 18.	0.453
Fbxw2	MED31	G5CAF5	G5B909	F-box/WD repeat-containing protein 2.	Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.458
Fbxw2	Rnf14	G5CAF5	G5AQR5	F-box/WD repeat-containing protein 2.	RBR-type E3 ubiquitin transferase.	0.419
GW7_21478	Rnf14	G5AV30	G5AQR5	Androgen receptor.	RBR-type E3 ubiquitin transferase.	0.687
Gspt1	Gspt2	G5B4G3	G5C143	Eukaryotic peptide chain release factor GTP-binding subunit ERF3A.	Eukaryotic peptide chain release factor GTP-binding subunit ERF3B.	0.910
Gspt1	Rnf14	G5B4G3	G5AQR5	Eukaryotic peptide chain release factor GTP-binding subunit ERF3A.	RBR-type E3 ubiquitin transferase.	0.435
Gspt2	Gspt1	G5C143	G5B4G3	Eukaryotic peptide chain release factor GTP-binding subunit ERF3B.	Eukaryotic peptide chain release factor GTP-binding subunit ERF3A.	0.910
Gspt2	Rnf14	G5C143	G5AQR5	Eukaryotic peptide chain release factor GTP-binding subunit ERF3B.	RBR-type E3 ubiquitin transferase.	0.435
MED31	Fbxo18	G5B909	G5BP97	Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	F-box only protein 18.	0.500
MED31	Fbxw2	G5B909	G5CAF5	Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	F-box/WD repeat-containing protein 2.	0.458