STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GW7_05506RAD51-associated protein 1. (272 aa)    
Predicted Functional Partners:
GW7_18717
DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]
   
 0.961
Wrn
Werner syndrome ATP-dependent helicase.
   
 
 0.942
Wdr48
WD repeat-containing protein 48.
    
 
 0.910
Exo1
Exonuclease 1.
   
 
 0.895
Palb2
Partner and localizer of BRCA2.
   
 0.813
GW7_18278
DNA repair protein RAD51-like protein 4.
   
 0.773
GW7_01311
DNA repair protein RAD51-like protein 2.
   
 0.743
Rad51b
DNA repair protein RAD51-like protein 2.
   
 0.743
GW7_18870
DNA repair protein XRCC3.
   
 0.736
GW7_16627
Condensin complex subunit 3.
   
  
 0.723
Your Current Organism:
Heterocephalus glaber
NCBI taxonomy Id: 10181
Other names: H. glaber, naked mole rat, naked mole-rat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.