Mchr1 protein (Heterocephalus glaber) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

Mchr1

Melanin-concentrating hormone receptor 1. (353 aa)

Predicted Functional Partners:

PMCH

0.988

BBS1

0.708

Bbs2

0.674

Bbs4

0.666

Bbs7

0.604

Smo

0.560

BBS5

0.542

GW7_06960

0.540

Ppp1r18

0.535

Carns1

0.533

Your Current Organism:

Heterocephalus glaber

NCBI taxonomy Id: 10181
Other names: H. glaber, naked mole rat, naked mole-rat

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BBS1	BBS5	G5BWY4	G5C8Q6	Bardet-Biedl syndrome 1 protein.	Bardet-Biedl syndrome 5 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the gua [...]	0.986
BBS1	Bbs2	G5BWY4	G5BMR9	Bardet-Biedl syndrome 1 protein.	Bardet-Biedl syndrome 2 protein homolog.	0.992
BBS1	Bbs4	G5BWY4	G5BRE7	Bardet-Biedl syndrome 1 protein.	Bardet-Biedl syndrome 4 protein.	0.995
BBS1	Bbs7	G5BWY4	G5BBT2	Bardet-Biedl syndrome 1 protein.	Bardet-Biedl syndrome 7 protein.	0.991
BBS1	GW7_06960	G5BWY4	G5AKE4	Bardet-Biedl syndrome 1 protein.	Protein PTHB1.	0.996
BBS1	Mchr1	G5BWY4	G5AYW7	Bardet-Biedl syndrome 1 protein.	Melanin-concentrating hormone receptor 1.	0.708
BBS1	Smo	G5BWY4	G5BH88	Bardet-Biedl syndrome 1 protein.	Smoothened-like protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.784
BBS5	BBS1	G5C8Q6	G5BWY4	Bardet-Biedl syndrome 5 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the gua [...]	Bardet-Biedl syndrome 1 protein.	0.986
BBS5	Bbs2	G5C8Q6	G5BMR9	Bardet-Biedl syndrome 5 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the gua [...]	Bardet-Biedl syndrome 2 protein homolog.	0.984
BBS5	Bbs4	G5C8Q6	G5BRE7	Bardet-Biedl syndrome 5 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the gua [...]	Bardet-Biedl syndrome 4 protein.	0.976
BBS5	Bbs7	G5C8Q6	G5BBT2	Bardet-Biedl syndrome 5 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the gua [...]	Bardet-Biedl syndrome 7 protein.	0.982
BBS5	GW7_06960	G5C8Q6	G5AKE4	Bardet-Biedl syndrome 5 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the gua [...]	Protein PTHB1.	0.986
BBS5	Mchr1	G5C8Q6	G5AYW7	Bardet-Biedl syndrome 5 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the gua [...]	Melanin-concentrating hormone receptor 1.	0.542
BBS5	Smo	G5C8Q6	G5BH88	Bardet-Biedl syndrome 5 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the gua [...]	Smoothened-like protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.496
Bbs2	BBS1	G5BMR9	G5BWY4	Bardet-Biedl syndrome 2 protein homolog.	Bardet-Biedl syndrome 1 protein.	0.992
Bbs2	BBS5	G5BMR9	G5C8Q6	Bardet-Biedl syndrome 2 protein homolog.	Bardet-Biedl syndrome 5 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the gua [...]	0.984
Bbs2	Bbs4	G5BMR9	G5BRE7	Bardet-Biedl syndrome 2 protein homolog.	Bardet-Biedl syndrome 4 protein.	0.992
Bbs2	Bbs7	G5BMR9	G5BBT2	Bardet-Biedl syndrome 2 protein homolog.	Bardet-Biedl syndrome 7 protein.	0.996
Bbs2	GW7_06960	G5BMR9	G5AKE4	Bardet-Biedl syndrome 2 protein homolog.	Protein PTHB1.	0.995
Bbs2	Mchr1	G5BMR9	G5AYW7	Bardet-Biedl syndrome 2 protein homolog.	Melanin-concentrating hormone receptor 1.	0.674