STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Plcd4Phosphoinositide phospholipase C. (816 aa)    
Predicted Functional Partners:
Pip4k2a
Phosphatidylinositol-5-phosphate 4-kinase type-2 alpha.
   
 0.927
Pip4k2c
Phosphatidylinositol-5-phosphate 4-kinase type-2 gamma.
   
 0.927
Pip5k1a
Phosphatidylinositol-4-phosphate 5-kinase type-1 alpha.
   
 0.925
Inpp5a
Type I inositol-1,4,5-trisphosphate 5-phosphatase.
   
 
 0.921
Pi4kb
Phosphatidylinositol 4-kinase beta; Belongs to the PI3/PI4-kinase family.
     
 0.912
Itpr2
Inositol 1,4,5-trisphosphate receptor type 2.
   
 
 0.912
Plcd1
Phosphoinositide phospholipase C.
  
  
0.910
Prkcb
Protein kinase C beta type; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
   
 
 0.910
CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase.
     
 0.910
Pik3cg
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; Belongs to the PI3/PI4-kinase family.
     
 0.910
Your Current Organism:
Heterocephalus glaber
NCBI taxonomy Id: 10181
Other names: H. glaber, naked mole rat, naked mole-rat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.