STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Gprasp1G-protein coupled receptor-associated sorting protein 1. (1384 aa)    
Predicted Functional Partners:
Tcf25
Transcription factor 25.
    
 
 0.718
Ptgr2
Prostaglandin reductase 2.
   
 
 0.562
Atg16l2
Autophagy-related protein 16-2.
    
 
 0.542
Gak
Cyclin G-associated kinase.
    
 0.453
GW7_11613
Protein BEX1.
  
 
 0.439
GW7_12697
AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]
    
  0.415
GW7_04579
AP-2 complex subunit mu; Belongs to the adaptor complexes medium subunit family.
    
  0.403
GW7_17237
AP-2 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.
    
  0.403
Ndufa6
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6; Belongs to the complex I LYR family.
    
 0.401
Your Current Organism:
Heterocephalus glaber
NCBI taxonomy Id: 10181
Other names: H. glaber, naked mole rat, naked mole-rat
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