STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Krt14Keratin, type I cytoskeletal 14; Belongs to the intermediate filament family. (439 aa)    
Predicted Functional Partners:
Krt5
Keratin, type II cytoskeletal 5; Belongs to the intermediate filament family.
  
0.989
Krt36
Keratin, type I cuticular Ha6; Belongs to the intermediate filament family.
  
 
0.704
Krt16
Keratin, type I cytoskeletal 16; Belongs to the intermediate filament family.
  
 
 
0.695
Unc79
Unc-79-like protein.
    
 0.665
GW7_16394
Unc-79-like protein.
    
 0.665
Col17a1
Collagen alpha-1(XVII) chain.
   
 0.519
Tp63
Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes.
   
 0.504
GW7_05154
E3 SUMO-protein ligase RanBP2.
   
 0.499
Krt15
Keratin, type I cytoskeletal 15; Belongs to the intermediate filament family.
  
 
 
0.493
GW7_06876
Keratin, type I cytoskeletal 42; Belongs to the intermediate filament family.
  
 
 
0.477
Your Current Organism:
Heterocephalus glaber
NCBI taxonomy Id: 10181
Other names: H. glaber, naked mole rat, naked mole-rat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.