GW7_19083 protein (Heterocephalus glaber) - STRING interaction network

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Score

GW7_19083

UV excision repair protein RAD23-like protein B. (140 aa)

Predicted Functional Partners:

Mysm1

0.967

GW7_05986

0.926

Ngly1

0.916

GW7_10557

0.892

Psmd2

0.849

Ubxn7

0.845

GW7_00042

0.825

Ube2v1

0.825

Traf7

0.819

ASNA1

0.806

Your Current Organism:

Heterocephalus glaber

NCBI taxonomy Id: 10181
Other names: H. glaber, naked mole rat, naked mole-rat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASNA1	GW7_19083	G5BYX4	G5B173	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	UV excision repair protein RAD23-like protein B.	0.806
GW7_00042	GW7_19083	G5AL98	G5B173	Ubiquitin-conjugating enzyme E2 variant 1.	UV excision repair protein RAD23-like protein B.	0.825
GW7_00042	Psmd2	G5AL98	G5BTC4	Ubiquitin-conjugating enzyme E2 variant 1.	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.	0.425
GW7_00042	Traf7	G5AL98	G5BY44	Ubiquitin-conjugating enzyme E2 variant 1.	E3 ubiquitin-protein ligase TRAF7.	0.721
GW7_00042	Ube2v1	G5AL98	G5AZ04	Ubiquitin-conjugating enzyme E2 variant 1.	Transmembrane protein 189.	0.849
GW7_05986	GW7_19083	G5ANS4	G5B173	DNA repair protein complementing XP-C cells.	UV excision repair protein RAD23-like protein B.	0.926
GW7_05986	Ngly1	G5ANS4	G5BF99	DNA repair protein complementing XP-C cells.	Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase.	0.533
GW7_10557	GW7_19083	G5AJZ8	G5B173	26S proteasome non-ATPase regulatory subunit 4.	UV excision repair protein RAD23-like protein B.	0.892
GW7_10557	Mysm1	G5AJZ8	G5APP0	26S proteasome non-ATPase regulatory subunit 4.	Histone H2A deubiquitinase MYSM1.	0.941
GW7_10557	Psmd2	G5AJZ8	G5BTC4	26S proteasome non-ATPase regulatory subunit 4.	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.	0.999
GW7_10557	Traf7	G5AJZ8	G5BY44	26S proteasome non-ATPase regulatory subunit 4.	E3 ubiquitin-protein ligase TRAF7.	0.435
GW7_10557	Ubxn7	G5AJZ8	G5ALB9	26S proteasome non-ATPase regulatory subunit 4.	UBX domain-containing protein 7.	0.949
GW7_19083	ASNA1	G5B173	G5BYX4	UV excision repair protein RAD23-like protein B.	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	0.806
GW7_19083	GW7_00042	G5B173	G5AL98	UV excision repair protein RAD23-like protein B.	Ubiquitin-conjugating enzyme E2 variant 1.	0.825
GW7_19083	GW7_05986	G5B173	G5ANS4	UV excision repair protein RAD23-like protein B.	DNA repair protein complementing XP-C cells.	0.926
GW7_19083	GW7_10557	G5B173	G5AJZ8	UV excision repair protein RAD23-like protein B.	26S proteasome non-ATPase regulatory subunit 4.	0.892
GW7_19083	Mysm1	G5B173	G5APP0	UV excision repair protein RAD23-like protein B.	Histone H2A deubiquitinase MYSM1.	0.967
GW7_19083	Ngly1	G5B173	G5BF99	UV excision repair protein RAD23-like protein B.	Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase.	0.916
GW7_19083	Psmd2	G5B173	G5BTC4	UV excision repair protein RAD23-like protein B.	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.	0.849
GW7_19083	Traf7	G5B173	G5BY44	UV excision repair protein RAD23-like protein B.	E3 ubiquitin-protein ligase TRAF7.	0.819