STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Synj1Synaptojanin-1. (1574 aa)    
Predicted Functional Partners:
Inpp4a
Type I inositol-3,4-bisphosphate 4-phosphatase.
     
 0.927
Sacm1l
Phosphatidylinositide phosphatase SAC1.
    
0.926
GW7_13987
Intersectin-2.
    
 
 0.921
Pi4ka
Phosphatidylinositol 4-kinase alpha.
     
 0.920
Pi4kb
Phosphatidylinositol 4-kinase beta; Belongs to the PI3/PI4-kinase family.
    
 0.919
Pten
Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.
     
 0.915
Pip5k1a
Phosphatidylinositol-4-phosphate 5-kinase type-1 alpha.
    
 0.913
Pip4k2a
Phosphatidylinositol-5-phosphate 4-kinase type-2 alpha.
    
 0.912
Pip4k2c
Phosphatidylinositol-5-phosphate 4-kinase type-2 gamma.
    
 0.912
INPP4B
Type II inositol 3,4-bisphosphate 4-phosphatase.
     
 0.912
Your Current Organism:
Heterocephalus glaber
NCBI taxonomy Id: 10181
Other names: H. glaber, naked mole rat, naked mole-rat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.