STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ankk1Ankyrin repeat and protein kinase domain-containing protein 1. (708 aa)    
Predicted Functional Partners:
GW7_02492
Tetratricopeptide repeat protein 12.
 
  
 0.699
GW7_02490
D(2) dopamine receptor; Belongs to the G-protein coupled receptor 1 family.
     
 0.633
Cd247
T-cell surface glycoprotein CD3 eta chain.
   
 0.608
Tab1
Mitogen-activated protein kinase kinase kinase 7-interacting protein 1.
   
 0.604
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.603
Tomt
Transmembrane O-methyltransferase.
      
 0.574
GW7_18221
Tryptophan 5-hydroxylase 2.
    
 
 0.570
GW7_21669
E3 ubiquitin-protein ligase MIB2.
   
0.562
Oprm1
Mu-type opioid receptor; Belongs to the G-protein coupled receptor 1 family.
     
 0.559
Fadd
FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.
   
 0.541
Your Current Organism:
Heterocephalus glaber
NCBI taxonomy Id: 10181
Other names: H. glaber, naked mole rat, naked mole-rat
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