STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pms2Mismatch repair endonuclease PMS2. (870 aa)    
Predicted Functional Partners:
Mlh1
DNA mismatch repair protein Mlh1.
    
0.999
Msh6
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
  
 0.996
MSH2
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
 
 0.995
Exo1
Exonuclease 1.
   
 0.981
Brip1
Fanconi anemia group J protein.
   
 0.972
Fan1
Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.
   
 0.970
GW7_10881
DNA mismatch repair protein Msh3.
 
 0.954
Msh4
MutS protein-like protein 4.
  
 0.936
Msh5
MutS protein-like protein 5.
  
 0.936
GW7_01393
Proliferating cell nuclear antigen.
   
 0.862
Your Current Organism:
Heterocephalus glaber
NCBI taxonomy Id: 10181
Other names: H. glaber, naked mole rat, naked mole-rat
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