STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GW7_08777Integrin-linked kinase-associated serine/threonine phosphatase 2C. (457 aa)    
Predicted Functional Partners:
GW7_04619
Glycolipid transfer protein domain-containing protein 2.
     
 0.614
OSGIN1
Oxidative stress-induced growth inhibitor 1.
    
 
 0.573
GW7_04618
Proteasome subunit beta type-6.
      
 0.534
Fam131a
Protein FAM131A.
      
 0.513
Med14
Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
   
 
 0.463
Mtfmt
Methionyl-tRNA formyltransferase, mitochondrial.
  
   0.459
Traf7
E3 ubiquitin-protein ligase TRAF7.
   
 0.456
MED31
Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
   0.449
ILK
Integrin-linked protein kinase.
   
 
 0.436
BCKDHB
2-oxoisovalerate dehydrogenase subunit beta, mitochondrial.
    
 0.424
Your Current Organism:
Heterocephalus glaber
NCBI taxonomy Id: 10181
Other names: H. glaber, naked mole rat, naked mole-rat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.