Bik protein (Heterocephalus glaber) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

Bik

Bcl-2-interacting killer. (186 aa)

Predicted Functional Partners:

Bcl2

0.987

BCL2L1

0.913

Bcl2l2

0.873

GW7_20578

0.664

Bok

0.629

Bcl2a1

0.585

Bcl2l11

0.581

Bard1

0.552

GW7_07849

0.544

GW7_00583

0.466

Your Current Organism:

Heterocephalus glaber

NCBI taxonomy Id: 10181
Other names: H. glaber, naked mole rat, naked mole-rat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCL2L1	Bcl2	G5BQH7	G5BGZ7	Bcl-2-like protein 1 isoform 2.	Apoptosis regulator Bcl-2.	0.992
BCL2L1	Bcl2l11	G5BQH7	G5BQZ0	Bcl-2-like protein 1 isoform 2.	Bcl-2-like protein 11.	0.999
BCL2L1	Bcl2l2	G5BQH7	G5ASL3	Bcl-2-like protein 1 isoform 2.	Bcl-2-like protein 2.	0.646
BCL2L1	Bik	G5BQH7	G5BM80	Bcl-2-like protein 1 isoform 2.	Bcl-2-interacting killer.	0.913
BCL2L1	GW7_20578	G5BQH7	G5BRJ4	Bcl-2-like protein 1 isoform 2.	Induced myeloid leukemia cell differentiation protein Mcl-1-like protein.	0.566
Bard1	Bik	G5BHR8	G5BM80	BRCA1-associated RING domain protein 1.	Bcl-2-interacting killer.	0.552
Bard1	GW7_07849	G5BHR8	G5BN95	BRCA1-associated RING domain protein 1.	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]	0.997
Bcl2	BCL2L1	G5BGZ7	G5BQH7	Apoptosis regulator Bcl-2.	Bcl-2-like protein 1 isoform 2.	0.992
Bcl2	Bcl2l11	G5BGZ7	G5BQZ0	Apoptosis regulator Bcl-2.	Bcl-2-like protein 11.	0.996
Bcl2	Bcl2l2	G5BGZ7	G5ASL3	Apoptosis regulator Bcl-2.	Bcl-2-like protein 2.	0.757
Bcl2	Bik	G5BGZ7	G5BM80	Apoptosis regulator Bcl-2.	Bcl-2-interacting killer.	0.987
Bcl2	Bok	G5BGZ7	G5C3S0	Apoptosis regulator Bcl-2.	Bcl-2-related ovarian killer protein.	0.508
Bcl2	GW7_07849	G5BGZ7	G5BN95	Apoptosis regulator Bcl-2.	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]	0.415
Bcl2	GW7_20578	G5BGZ7	G5BRJ4	Apoptosis regulator Bcl-2.	Induced myeloid leukemia cell differentiation protein Mcl-1-like protein.	0.551
Bcl2a1	Bcl2l11	G5BEY0	G5BQZ0	Bcl-2-related protein A1.	Bcl-2-like protein 11.	0.958
Bcl2a1	Bik	G5BEY0	G5BM80	Bcl-2-related protein A1.	Bcl-2-interacting killer.	0.585
Bcl2l11	BCL2L1	G5BQZ0	G5BQH7	Bcl-2-like protein 11.	Bcl-2-like protein 1 isoform 2.	0.999
Bcl2l11	Bcl2	G5BQZ0	G5BGZ7	Bcl-2-like protein 11.	Apoptosis regulator Bcl-2.	0.996
Bcl2l11	Bcl2a1	G5BQZ0	G5BEY0	Bcl-2-like protein 11.	Bcl-2-related protein A1.	0.958
Bcl2l11	Bcl2l2	G5BQZ0	G5ASL3	Bcl-2-like protein 11.	Bcl-2-like protein 2.	0.973