STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GW7_04847Protein-L-isoaspartate(D-aspartate) O-methyltransferase. (336 aa)    
Predicted Functional Partners:
Ttc7b
Tetratricopeptide repeat protein 7B.
      
 0.677
LOH12CR1
Loss of heterozygosity 12 chromosomal region 1 protein.
   
  
 0.601
METTL6
Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family.
      
 0.551
Uhrf1
E3 ubiquitin-protein ligase UHRF1.
      
 0.540
RNF13
E3 ubiquitin-protein ligase RNF13.
      
 0.479
GW7_12851
Transmembrane protein 183.
      
 0.474
KATNA1
Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal p [...]
   
  
 0.474
GW7_18575
Tetratricopeptide repeat protein 7A.
      
 0.473
GW7_08766
Nogo-B receptor.
     
 0.466
Sod2
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
  
 0.459
Your Current Organism:
Heterocephalus glaber
NCBI taxonomy Id: 10181
Other names: H. glaber, naked mole rat, naked mole-rat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.