STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Snta1Alpha-1-syntrophin. (505 aa)    
Predicted Functional Partners:
Dmd
Dystrophin.
    
 
 0.915
GW7_04524
Dystrobrevin alpha.
    
 
 0.765
GW7_10846
Utrophin.
    
 
 0.750
GW7_18334
Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein.
    
 
 0.707
GW7_14087
FERM and PDZ domain-containing protein 2.
      
 0.678
Dag1
Dystroglycan.
    
 
 0.655
CAV3
Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.
   
  
 0.648
Scn5a
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
    
 
 0.636
Fbxo21
Nitric oxide synthase, brain.
    
 
 0.631
Nos3
Nitric oxide synthase; Produces nitric oxide (NO).
    
 
 0.631
Your Current Organism:
Heterocephalus glaber
NCBI taxonomy Id: 10181
Other names: H. glaber, naked mole rat, naked mole-rat
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