STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GW7_14197Lipin-1. (879 aa)    
Predicted Functional Partners:
CTDNEP1
Serine/threonine-protein phosphatase dullard.
    
 0.871
GW7_21348
Lipin-3.
  
 
 
0.787
Ppargc1a
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha.
      
 0.694
GW7_21373
Lipin-2.
  
 
 
0.675
Ppara
Peroxisome proliferator-activated receptor alpha.
    
 
 0.667
Cnep1r1
Transmembrane protein 188.
     
 0.612
UBLCP1
Ubiquitin-like domain-containing CTD phosphatase 1.
    
 0.596
PPARG
Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]
    
 
 0.581
GW7_07361
CTD small phosphatase-like protein.
    
 0.574
GW7_15238
CTD small phosphatase-like protein 2.
    
 0.574
Your Current Organism:
Heterocephalus glaber
NCBI taxonomy Id: 10181
Other names: H. glaber, naked mole rat, naked mole-rat
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.