STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (95 aa)    
Predicted Functional Partners:
Cxcl1
C-X-C motif chemokine.
   
 
0.977
Cxcr1
High affinity interleukin-8 receptor A.
   
 
 0.956
Cxcr2
High affinity interleukin-8 receptor B; Belongs to the G-protein coupled receptor 1 family.
   
 
 0.955
Agtr1
Type-1 angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family.
     
  0.921
F2r
Proteinase-activated receptor 1; Belongs to the G-protein coupled receptor 1 family.
     
  0.905
Lpar1
Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family.
     
 0.904
Rela
Transcription factor p65.
   
 
 0.903
Lpar5
Lysophosphatidic acid receptor 5; Belongs to the G-protein coupled receptor 1 family.
   
 
  0.903
AVPR1A
Vasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
     
  0.902
Ptgfr
Prostaglandin F2-alpha receptor; Belongs to the G-protein coupled receptor 1 family.
     
  0.902
Your Current Organism:
Heterocephalus glaber
NCBI taxonomy Id: 10181
Other names: H. glaber, naked mole rat, naked mole-rat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.