STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GW7_13287Low-density lipoprotein receptor. (894 aa)    
Predicted Functional Partners:
LDLRAP1
Low density lipoprotein receptor adapter protein 1.
    
 0.935
GW7_13512
Proprotein convertase subtilisin/kexin type 9.
    
 0.859
Reln
Reelin.
    
 0.858
Mylip
E3 ubiquitin-protein ligase MYLIP.
    
 0.721
GW7_13987
Intersectin-2.
    
 0.692
Apob
Apolipoprotein B-100.
    
 0.671
HMGCS1
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
   
  
 0.655
DKK1
Dickkopf-related protein 1.
    
 0.616
GW7_21696
Agrin.
    
 0.584
Hspg2
Basement membrane-specific heparan sulfate proteoglycan core protein.
    
0.576
Your Current Organism:
Heterocephalus glaber
NCBI taxonomy Id: 10181
Other names: H. glaber, naked mole rat, naked mole-rat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.