STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GW7_21611Fibroblast growth factor-binding protein 3. (133 aa)    
Predicted Functional Partners:
Znf592
Zinc finger protein 592.
      
 0.538
Slc25a37
Mitoferrin-1; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.487
Hdhd3
Haloacid dehalogenase-like hydrolase domain-containing protein 3.
      
 0.465
B4GALT3
Beta-1,4-galactosyltransferase 3.
      
 0.450
Fgf10
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
     
 0.434
GW7_08102
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
     
 0.434
FGF1
Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]
     
 0.433
Fgf7
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
     
 0.433
Ttyh1
Protein tweety homolog; Probable chloride channel; Belongs to the tweety family.
      
 0.426
GW7_18955
Fibroblast growth factor receptor 3.
     
 0.409
Your Current Organism:
Heterocephalus glaber
NCBI taxonomy Id: 10181
Other names: H. glaber, naked mole rat, naked mole-rat
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.