STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Erp27Endoplasmic reticulum resident protein ERp27. (275 aa)    
Predicted Functional Partners:
Gak
Cyclin G-associated kinase.
    
 0.755
GW7_18775
Protein disulfide-isomerase.
   
 0.678
Msra
Peptide methionine sulfoxide reductase.
   
 0.652
HSPA5
78 kDa glucose-regulated protein; Belongs to the heat shock protein 70 family.
   
 0.590
Prdx5
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
   
 0.552
GW7_18544
Hepatocyte nuclear factor 3-alpha.
    
 
 0.544
Ero1b
ERO1-like protein beta.
   
 0.529
Ero1a
ERO1-like protein alpha.
   
 0.529
GW7_01514
Putative tyrosine-protein phosphatase auxilin.
    
 0.522
PDIA4
Protein disulfide-isomerase A4.
   
 0.502
Your Current Organism:
Heterocephalus glaber
NCBI taxonomy Id: 10181
Other names: H. glaber, naked mole rat, naked mole-rat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.