STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GW7_16485annotation not available (187 aa)    
Predicted Functional Partners:
GW7_08972
Ubiquitin carboxyl-terminal hydrolase 7; Belongs to the peptidase C19 family.
   
 0.829
Sprtn
Uncharacterized protein.
   
    0.820
WWP2
E3 ubiquitin-protein ligase.
   
 0.756
GW7_05498
E3 ubiquitin-protein ligase NEDD4.
    
 0.755
Mast2
Microtubule-associated serine/threonine-protein kinase 2.
    
 
 0.753
Tp53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
   
 0.724
Usp13
Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.
    
 0.712
GW7_05183
Neuronal acetylcholine receptor subunit beta-2.
      
 0.681
GW7_06072
Palmitoyl-protein thioesterase 1.
      
 0.681
Nmur2
Neuromedin-U receptor 2; Belongs to the G-protein coupled receptor 1 family.
      
 0.678
Your Current Organism:
Heterocephalus glaber
NCBI taxonomy Id: 10181
Other names: H. glaber, naked mole rat, naked mole-rat
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.