STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CebpaCCAAT/enhancer-binding protein alpha. (143 aa)    
Predicted Functional Partners:
Per2
Period circadian protein-like protein 2.
   
 0.925
Flt3
FL cytokine receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
     
 0.923
CDK4
Cell division protein kinase 4; Belongs to the protein kinase superfamily.
    
 0.760
CDK2
Cyclin-dependent kinase 2 isoform 1; Belongs to the protein kinase superfamily.
    
 0.751
GW7_01865
Cytochrome c oxidase subunit 5A, mitochondrial.
   
 0.700
GW7_00817
DUF4706 domain-containing protein.
   
 0.680
GW7_06435
Cell division protein kinase 3.
    
 0.659
COX2
Cytochrome c oxidase subunit 2; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1.
    
 0.650
Cdk6
Cell division protein kinase 6; Belongs to the protein kinase superfamily.
    
 0.631
Cdkn1a
Cyclin-dependent kinase inhibitor 1.
   
 0.616
Your Current Organism:
Heterocephalus glaber
NCBI taxonomy Id: 10181
Other names: H. glaber, naked mole rat, naked mole-rat
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.