node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Esrra | GW7_11332 | G5B6P9 | G5ATT4 | Steroid hormone receptor ERR1. | Estrogen-related receptor gamma. | 0.620 |
Esrra | GW7_11769 | G5B6P9 | G5C8V3 | Steroid hormone receptor ERR1. | Estrogen-related receptor gamma. | 0.618 |
Esrra | Nrf1 | G5B6P9 | G5BH83 | Steroid hormone receptor ERR1. | Nuclear respiratory factor 1. | 0.560 |
Esrra | PPARG | G5B6P9 | G5APJ1 | Steroid hormone receptor ERR1. | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | 0.580 |
Esrra | Ppargc1b | G5B6P9 | G5C3A1 | Steroid hormone receptor ERR1. | Peroxisome proliferator-activated receptor gamma coactivator 1-beta. | 0.859 |
Esrra | Srebf1 | G5B6P9 | G5BMW6 | Steroid hormone receptor ERR1. | Sterol regulatory element-binding protein 1. | 0.588 |
GW7_11332 | Esrra | G5ATT4 | G5B6P9 | Estrogen-related receptor gamma. | Steroid hormone receptor ERR1. | 0.620 |
GW7_11332 | Ppargc1b | G5ATT4 | G5C3A1 | Estrogen-related receptor gamma. | Peroxisome proliferator-activated receptor gamma coactivator 1-beta. | 0.616 |
GW7_11769 | Esrra | G5C8V3 | G5B6P9 | Estrogen-related receptor gamma. | Steroid hormone receptor ERR1. | 0.618 |
GW7_11769 | Ppargc1b | G5C8V3 | G5C3A1 | Estrogen-related receptor gamma. | Peroxisome proliferator-activated receptor gamma coactivator 1-beta. | 0.616 |
GW7_18476 | NCBP2 | G5C1C6 | G5ALD0 | Nuclear cap-binding protein subunit 1. | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] | 0.999 |
GW7_18476 | Ppargc1b | G5C1C6 | G5C3A1 | Nuclear cap-binding protein subunit 1. | Peroxisome proliferator-activated receptor gamma coactivator 1-beta. | 0.790 |
NCBP2 | GW7_18476 | G5ALD0 | G5C1C6 | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] | Nuclear cap-binding protein subunit 1. | 0.999 |
NCBP2 | Ppargc1b | G5ALD0 | G5C3A1 | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] | Peroxisome proliferator-activated receptor gamma coactivator 1-beta. | 0.611 |
Nrf1 | Esrra | G5BH83 | G5B6P9 | Nuclear respiratory factor 1. | Steroid hormone receptor ERR1. | 0.560 |
Nrf1 | Ppargc1b | G5BH83 | G5C3A1 | Nuclear respiratory factor 1. | Peroxisome proliferator-activated receptor gamma coactivator 1-beta. | 0.824 |
PPARG | Esrra | G5APJ1 | G5B6P9 | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | Steroid hormone receptor ERR1. | 0.580 |
PPARG | Ppargc1b | G5APJ1 | G5C3A1 | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | Peroxisome proliferator-activated receptor gamma coactivator 1-beta. | 0.623 |
PPARG | Srebf1 | G5APJ1 | G5BMW6 | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | Sterol regulatory element-binding protein 1. | 0.711 |
Pdk4 | Ppara | G5AJS6 | G5BVA9 | Protein-serine/threonine kinase. | Peroxisome proliferator-activated receptor alpha. | 0.541 |