STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (152 aa)    
Predicted Functional Partners:
Il2ra
Interleukin-2 receptor alpha chain.
    
 0.997
Il2rb
Interleukin-2 receptor subunit beta.
    
 0.996
Il4
Interleukin-4.
   
 
 0.982
Il7
Interleukin-7.
  
  
 0.981
IL6
Interleukin-6.
     
 0.976
CSF3
Granulocyte colony-stimulating factor isoform a.
   
 
 0.964
Ifnb1
Interferon beta.
     
 0.935
GW7_09531
Interferon alpha-4.
     
 0.919
GW7_10718
Cytokine receptor common gamma chain.
    
 0.912
GW7_19202
Cytokine receptor common gamma chain.
    
 0.912
Your Current Organism:
Heterocephalus glaber
NCBI taxonomy Id: 10181
Other names: H. glaber, naked mole rat, naked mole-rat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.