STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HhipHedgehog-interacting protein. (699 aa)    
Predicted Functional Partners:
DHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.997
Ihh
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.995
Sorl1
Sortilin-related receptor.
    
 0.834
Gli1
Zinc finger protein GLI1.
      
 0.725
Ptch1
Patched-like protein 1.
    
 
 0.673
Sh3gl3
Endophilin-A3.
    
 
 0.600
F2r
Proteinase-activated receptor 1; Belongs to the G-protein coupled receptor 1 family.
    
 0.583
Dym
Dymeclin.
      
 0.565
Ctdsp2
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2.
      
 0.556
Smo
Smoothened-like protein; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.550
Your Current Organism:
Heterocephalus glaber
NCBI taxonomy Id: 10181
Other names: H. glaber, naked mole rat, naked mole-rat
Server load: low (24%) [HD]