STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GW7_12101CD27 antigen. (256 aa)    
Predicted Functional Partners:
GW7_20470
CD70 antigen; Belongs to the tumor necrosis factor family.
    
 0.971
Cd19
B-lymphocyte antigen CD19.
   
  
 0.721
Cd38
ADP-ribosyl cyclase 1.
   
  
 0.704
GW7_13122
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 
 0.701
GW7_11053
T-lymphocyte activation antigen CD86.
   
  
 0.693
Tnfsf4
Tumor necrosis factor ligand superfamily member 4; Belongs to the tumor necrosis factor family.
      
 0.678
SIVA1
Apoptosis regulatory protein Siva; Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl- x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis.
    
 
 0.639
GW7_01742
T-cell surface glycoprotein CD5.
   
  
 0.627
Ccr7
C-C chemokine receptor type 7; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.623
Klrg1
Killer cell lectin-like receptor subfamily G member 1.
   
  
 0.609
Your Current Organism:
Heterocephalus glaber
NCBI taxonomy Id: 10181
Other names: H. glaber, naked mole rat, naked mole-rat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.