STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BpHYR1_004301Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (252 aa)    
Predicted Functional Partners:
BpHYR1_025367
DNA mismatch repair Mlh1-like.
   
 0.894
BpHYR1_012900
Mismatch repair endonuclease PMS2.
   
 0.865
BpHYR1_047671
Fanconi anemia group M isoform X1.
    
 0.846
BpHYR1_047678
Fanconi anemia group M.
    
 0.846
BpHYR1_007219
Fanconi anemia group D2.
    
 0.770
BpHYR1_035776
Fanconi anemia group D2 isoform X1.
    
 0.770
BpHYR1_027951
Fanconi anemia group D2.
    
 0.770
BpHYR1_007123
Fanconi anemia group I.
    
 0.750
BpHYR1_042238
DNA cross-link repair 1A.
    
 0.683
BpHYR1_017871
Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA; Belongs to the SLX1 family.
   
 
 0.679
Your Current Organism:
Brachionus plicatilis
NCBI taxonomy Id: 10195
Other names: B. plicatilis
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